MB 20 series
The Alfa Laval MB 20 series is designed for cell-harvesting centrifugation in pilot-scale research and small-scale manufacturing. MB 20 separators are specifically developed for gentle and highly efficient harvesting of biopharma and biotech fermentations, producing end products such as rDNA, vaccines, and probiotics. In addition, the MB 20 Bactofuge™ provides continuous solids removal, making it particularly suitable for high-concentration cultures.
Separator system for cell harvesting centrifugation, optimized for biopharma and biotech applications
- Efficient and gentle separation resulting in high yield
- Low lysis and high filterability, reducing costs of downstream filtration
- Enables continuous removal of solids up to 40% concentration in feed
- Accurate scalability from pilot scale to large-scale production
- Fully automated and flexible for process variations
The complex and delicate nature of cells requires careful handling to secure high yields and facilitate downstream filtering. Through continuous and highly efficient separation, MB 20 and MB 20 Bactofuge centrifuges bring improved productivity to biopharma applications at pilot scale.
The MB range of centrifuges incorporates unique Alfa Laval technologies, like Hermetic Design™ for enhanced product handling in various separation applications, and Bactofuge®, facilitating gentle but speedy processing of high-solids broths with continuous discharge of a highly concentrated solids phase. With these innovations, the MB centrifuges add profitability and offers unmatched scalability for biotech and biopharmaceutical pilot projects and small-scale production.
Innovative technology behind MB 20 series
Hermetic Design™
Alfa Laval Hermetic Design™ improves product handling in a wide range of separation applications. The air-tight and bottom-fed bowl enables gentle acceleration of media, with minimal foaming and oxygen pick-up, providing high product yield and low filter costs.
Bactofuge®
Alfa Laval Bactofuge® enables gentle and speedy continuous solids removal for high concentrations cultures, resulting in higher yield, with minimum risk of clogging. In addition to higher separation output, Bactofuge preserves the quality of the solids stream, and allows a flexible and controlled operation.
The MB 20 range of centrifuges for cell harvesting
Premium separation performance in a plug & play system. Fully automated and user-friendly operation for small-scale biopharma and biotech processing, with the option of Bactofuge® - providing continuous solids phase removal.
MB 20
- 2-phase clarification
- 50 - 600 l/h processing capacity
MB 20 Bactofuge
- 3-phase separation
- 50 - 600 l/h processing capacity
- Bactofuge®: continuous solids removal for high concentrations cultures
- With the optional conversion kit, you get 2-1 centrifuges, converting 3-phase to 2-phase clarification
Find out how the MB 20 series work
Do you want to learn more about MB 20? Watch our short animation and discover more.
Scalable performance
Services
Extending the performance of your equipment
For the market’s widest portfolio of heat transfer, separation and fluid handling equipment, Alfa Laval offers an unmatched range of services and support. From assistance during installation and commissioning to routine maintenance options and expertise to solve tough challenges, we are here to make sure your equipment delivers the performance you expect for a long time to come.
Our global network of service centers is staffed by maintenance technicians with extensive process and product knowledge. No matter where you are, we make sure you have a local contact who can be onsite with the experience to meet your needs.
Contact us to learn more.
Separation expertise for next-generation food
The world`s growing population deserves nutritious and tasty food, produced without harming our planet. The food landscape is changing, through groundbreaking research and cutting-edge technology. Alfa Laval provides unmatched separation expertise for this transformation: bringing scalability, profitability, and resource efficiency to next-generation food processes, like cellular agriculture.
The Separator Innovator
Would you like to know more about our innovations in separation technology? Click on the link below. Alfa Laval invented the first disc stack separator and has led the way in the development of centrifuge technology for over a century. We are glad to share with you the expertise we have gained along the way. Visit our Separator Innovator knowledge base to learn more about advancements in separation and the steps Alfa Laval is taking to continue revolutionizing the technology.